Frequently Asked Questions

What is this regenerative matrix made of? 

The base of our products is a regenerative matrix made from equine birth tissue.  After a foal is born, the birth tissues (e.g amniotic sac, related fluids, umbilical cord) are typically discarded.  However, when collected quickly, the full array of components that helped grow that foal from conception to birth can be preserved and utilized to regenerate healthy, adult equine tissue with minimal adhesions.

 

What are the components in the amniotic birth tissue?

The primary components that help a foal to grow in a healthy, structured manner include extracellular matrix, collagen, hyaluronic acid, cytokines, exosomes and microRNA.  These same components are what makeup Regenaflex™.

 

What do these components do when used in regenerative therapy? 

All of the components help up-regulate a horse’s own immune response to aid in the tissue healing process.  These components naturally exhibit anti-inflammatory, anti-microbial, anti-fibrotic and anti-adhesions properties thus allowing the body to heal itself with minimal scar tissue, reduced inflammation, minimal risk of infection and reduced re-injury rates. 

 

How do you procure your birth tissue? 

We work with reputable reproductive farms throughout the country to collect our tissues during live birth of a healthy foal from a healthy mare.  We do not collect any tissue by cesarean section.  No mares or foals are harmed in the process of collecting the birth tissue. 

 

Are the animals tested prior to collection? 

All mares are screened for medical and travel history prior to collection and acceptance.  When medical and travel history are acceptable, mares go through a strict testing procedure where the blood work is sent to a certified lab prior to collection of birth tissues.  The third party lab tests for tick borne illness, EIA and Brucella.  We follow all USDA guidelines and recommendations for vaccine and serum products for horses.

 

How does Regenaflex™ work? 

Regenaflex™ starts to work immediately after implantation of the products.  Where there is inflammation, Regenaflex™ will seek it out and help the body address what is causing the underlying issue creating the inflammation. 

 

How many treatments are required? 

Typically only one treatment is necessary for the implantation of the Regenaflex™.  However for large external wounds, several treatments may be needed as the wound heals. 

 

What are the risks with Regenaflex? 

There are no known risks associated with Regenaflex™ products.  No adverse reactions or significant side effects have been reported in the literature that we have seen.  As with many injections, side effects may include inflammation and irritation at the injection site.  If this occurs, it typically resolves within 1-3 days.  Continued movement will help the inflammation and irritation subside.

 

Can I give NSAIDs like Bute with Regenaflex?  

We recommend that the horse be taken off any NSAIDS just prior to use and for at least a week post treatment.  The inflammatory response is necessary to help repair injured tissues. 

 

What if I just gave a steroid injection, when can I use Regenaflex™? 

We recommend waiting 7-10 days post steroid injection before using Regenaflex™.  Steroids can have a negative impact on the healing potential of Regenaflex™ products. We recommend waiting to administer steroids for at least 30 days post Regenaflex™ treatment. 

 

What treatments can I use in conjunction with Regenaflex™? 

Treatments including shockwave therapy, ultrasound therapy, pool therapy, active rehabilitation may be used in conjunction with Regenaflex™. 

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 617-237-0636

info@hilltopbio.com

241 Francis Ave Mansfield, MA 02048